| Director of the Matenadaran, Dr. Vahan Ter-Ghevondian | +37410 513000 |
| Deputy Director of the Matenadaran on scientific work, Dr. Karen Matevosyan | +37410 513001 |
| Scientist Secretary, Dr. Vahe Torosyan | +37410 513012 |
| Deputy Director of Economic Affairs, Armen Mkrtchyan | +37410 513040 |
| Head of the Depositories, Dr. Gevorg Ter-Vardanean | +37410 513052 |
| Advisor to the Director Regarding Educational Programs Affairs, Dr. Haykaz Hovhannisyan | +37410 513013 |
| Advisor to the Director Regarding of New Technological and Publishing Affairs, Gurgen Gasparyan | +37410 513029 |
| Head of the Human Resources Department, Anahit Nshanyan | +37410 5130010 |
| Chief Accountant, Nvard Piltakyan | +37410 513003 |
| Head of the Department of International Relations, Vardi Keshishian | +37410 513049 |
| Head of the Public Relations Department, Tatevik Saroyan | +37410 513065 |
| Head of the Department for the Study of the History of Medicine and Science, Dr. Stella Vardanyan | +37410 513042 |
| Head of the Department for the Study of Translated Literature, Dr. Gohar Muradyan | +37410 513028 |
| Work coordinator of the Department of Oriental Studies, Dr. Vahan Ter-Ghevondian | +37410 513000 |
| Head of the Department for the Study of the Armenian Texts of the 5th–14th Centuries, Dr. Manya Shirinyan | +37410 513041 |
| Work coordinator of the Department for the Study of the Armenian Literature of the 15th–19th Centuries, Dr. Vahe Torosyan | +37410 513012 |
| Head of the Department of Philology and the Study of Secular Literature, Dr. Aram Topchyan | |
| Head of the Department of Study of Art History and Scriptoria, Dr. Karen Matevosyan | +37410 513001 |
| Head of the Department of Manuscript Studies, Dr. Gevorg Ter-Vardanyan | +37410 513052 |
| Head of the Department of the Archive and Archival Studies, Dr. Armen Malkhasyan | +37410 513020 |
| Head of the Museum Department, Ph.D. in Art History, Nazenie Garibian | +37410 513045 |
| Head of the Reading Hall, Janna Matevosyan | +37410 513056 |
| Head of the Library, Tatevik Ghazumyan | +37410 513030 |
| Head of the Department of Restoration, Gayane Eliazyan | +37410 510017 |
| Head of the Department of Manuscript Copying, Lilit Amirjanyan | |
| Coordinator of the Department of Digitization, Gurgen Gasparyan | +37410 513029 |
| Head of the Department of Publication, Dr. Hayk Hambardzumyan | +37410513033000000 |
