| Director of the Matenadaran, Dr. Vahan Ter-Ghevondyan | 010 513000 |
| Deputy Director of the Matenadaran on scientific work, Dr. Karen Matevosyan | 010 513001 |
| Scientist Secretary, Dr. Vahe Torosyan | 010 513012 |
| Deputy Director of Economic Affairs, Armen Mkrtchyan | 010 513040 |
| Head of the Depositories, Dr. Gevorg Ter-Vardanyan | 010 513052 |
| Advisor to the Director Regarding Educational Programs Affairs, Dr. Haykaz Hovhannisyan | 010 513013 |
| Advisor to the Director Regarding of New Technological and Publishing Affairs, Gurgen Gasparyan | 010 513029 |
| Head of the Human Resources Department, Anahit Nshanyan | 010 513010 |
| Chief Accountant, Nvard Piltakyan | 010 513003 |
| Head of the Department of International Relations, Vardi Keshishian | 010 513049 |
| Head of the Public Relations Department, Tatevik Saroyan | 010 513065 |
| Head of the Department for the Study of the History of Medicine and Science, Dr. Stella Vardanyan | 010 533042 |
| Head of the Department for the Study of Translated Literature, Dr. Gohar Muradyan | |
| Head of the Department of Oriental Studies, Dr. Vahan Ter-Ghevondian | 010 513000 |
| Head of the Department for the Study of the Armenian Texts of the 5th–14th Centuries, Dr. Manya Shirinyan | 010 513041 |
| Head of the Department for the Study of the Armenian Literature of the 15th–19th Centuries, Dr. Vahe Torosyan | 010 513012 |
| Head of the Department of Philology and the Study of Secular Literature, Dr. Aram Topchyan | |
| Head of the Department of Study of Art History and Scriptoria, Dr. Karen Matevosyan | 010 513001 |
| Head of the Department of Manuscript Studies, Dr. Gevorg Ter-Vardanyan | 010 513052 |
| Head of the Department of the Archive and Archival Studies, Dr. Armen Malkhasyan | 010 513020 |
| Head of the Department of Exhibition Halls, Aida Charkhchyan | 010 513045 |
| Head of the Reading Hall, Janna Matevosyan | 010 513056 |
| Head of the Library, Raya Blbulyan | 010 513030 |
| Head of the Department of Restoration, Gayane Eliazyan | 010 510017 |
| Head of the Department of Manuscript Copying, Lilit Amirjanyan | |
| Coordinator of the Department of Digitization, Gurgen Gasparyan | 010 513029 |
| Head of the Department of Publication, Dr. Hayk Hambardzumyan | 010513033000000 |
