| Director, Ph.D. in Arts Arayik Khzmalyan | +37410 513000 |
| Deputy Director of Scientific Affairs, Ph.D. in History Vahe Torosyan | +37410 513001 |
| Scientist Secretary, | +37410 513012 |
| Acting Deputy Director of Development, Tatevik Muradyan | +37410 513008 |
| Head of the Depository of Manuscripts, Ph.D. in Arts, David Ghazaryan | +37410 513052 |
| Head of the “Matenadaran Museum“, Ph.D. in Art History, Yvette Tajarian | +37410 513045 |
| Advisor to the Director Regarding Educational Programs Affairs, Doctor of History, Haykaz Hovhannisyan | +37410 513013 |
| Advisor to the Director Regarding of New Technologcs, Gurgen Gasparyan | +37410 513029 |
| Head of the Human Resources Department, Anahit Nshanyan | +374105130010 |
| Chief Accountant, Nvard Piltakyan | +37410 513003 |
| Head of the Development Group, Tatevik Muradyan | +37410 513008 |
| Head of the Public Relations Department, Emma Horopyan | +37410 513065 |
| Head of the Department for the Study of the History of Medicine and Science, | +37410 513042 |
| Head of the Department of Translated Literature, Doctor of Philology, Gohar Muradyan | +37410 513028 |
| Head of the Department of Oriental Studies, Doctor of History, Kristine Kostikyan | |
| Head of the Department for the Study of the Armenian Texts of the 5th–14th Centuries, Doctor of History, Manya Shirinyan | +37410 513041 |
| Head of the group of the Armenian Literature of the 15th–19th Centuries, Ph.D. in History, Anna Ohanjanyan | +37410 513000 |
| Head of the Department of Medieval Armenian Literature and Philology, Doctor of Philology, Aram Topchyan | |
| Head of the Department of Study of Scriptoria, Doctor of History, Karen Matevosyan | +37410 513042 |
| Work coordinator of the Department of Manuscript Studies, Gurgen Gasparyan | +37410 513029 |
| Head of the Departments of the Archive and Archival Studies, Ph.D. in History, Armen Malkhasyan | +37410 513020 |
| Head of the Reading Hall, Janna Matevosyan | +37410 513056 |
| Head of the Library, Tatevik Ghazumyan | +37410 513030 |
| Head of the Department of Restoration, Ph.D. in Chemical Sciences, Gayane Eliazyan | +37410 510017 |
| Coordinator of the Department of Digitization, Gurgen Gasparyan | +37410 513029 |
| Head of the Publishing House “Matenadaran”, Ph.D. in Philology, Hayk Hambardzumyan | +37410513033 |
| Head of the group of Biochemical Research of Manuscripts, Ph.D. in Chemical Sciences, Gayane Eliazyan | +37410 510017 |
